KMID : 0854720070270030200
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Korean Journal of Asthma, Allergy and Clinical Immunology 2007 Volume.27 No. 3 p.200 ~ p.203
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A Case of Adult Onset Cow¡¯s Milk Allergy Presenting Beef and Pork Meat Allergy
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Choi Sung-Jin
Hur Gyu-Young Park Hae-Sim Shin Seung-Youp
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Abstract
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Cow¡¯s milk has been recognized for many years as one of the leading causes of food allergy. The prevalence of cow¡¯s milk allergy is reported to be 1% to 2%. It has been reported that 13~20% of milk allergy children react to beef. We experienced a case of 47-year-old female patient presenting with severe food allergy symptoms including abdominal pain, dizziness, dyspnea, nasal stuffiness and vaginal spotting 2~3 hours after ingestion of cow¡¯s milk, beef, or pork which developed 8 months ago. Laboratory findings showed high total IgE levels (1,295 kU/L) and high specific IgE levels to milk, beef, and pork (3.04 kU/L, 9.26kU/L, and 4.58 kU/L, respectively) using the immuno-CAP system, while allergy skin tests for milk, beef, and pork showed negative results. In bovine serum albumin (BSA) IgE ELISA test, the patient showed a high serum specific IgE binding activity to the BSA compared to healthy controls. She received regular inhaled corticosteroid and antihistamines and restricted ingestion of cow¡¯s milk, beef and pork meats. We report a rare case of adult-onset milk allergy showing concurrent reactivity to beef and pork.
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KEYWORD
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Cow¡¯s milk allergy, Beef allergy, Bovine serum albumin, Cross reaction
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